Low-salt diet reduces anti-ctla4 mediated systemic immune-related adverse events while retaining therapeutic efficacy against breast cancer

HIGHLIGHTS

• who: Durga Khandekar et al. from the Department of Biological Sciences, Tennessee State University, Nashville, TN, USA have published the Article: Low-Salt Diet Reduces Anti-CTLA4 Mediated Systemic Immune-Related Adverse Events while Retaining Therapeutic Efficacy against Breast Cancer, in the Journal: (JOURNAL)
• what: We showed that an HS diet in combination with anti-CTLA4 mAb enhanced systemic irAE response.
• future: Studies are needed to study the impact of LS diet on other (non-CTLA4-based) ICI therapies on cancer immunotherapeutic efficacy and irAE incidence.

SUMMARY

Both the . . .

 



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