Low-solubility particles and a trojan-horse type mechanism of toxicity: the case of cobalt oxide on human lung cells

HIGHLIGHTS

  • who: ICP- et al. from the (UNIVERSITY) have published the article: Low-solubility particles and a Trojan-horse type mechanism of toxicity: the case of cobalt oxide on human lung cells, in the Journal: (JOURNAL)
  • what: The study shows that cobalt oxide particles of very low solubility in the culture medium are readily incorporated by BEAS-2B human lung cells through endocytosis via the clathrin-dependent pathway. The authors investigated cobalt oxide particle (Co3O4) toxicity on BEAS-2B human lung cells, and used high-sensitivity analytical techniques that allowed for the first time the discrimination . . .

     

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