Lps promotes a monocyte phenotype permissive for human cytomegalovirus immediate-early gene expression upon infection but not reactivation from latency

HIGHLIGHTS

• who: V. G. Kew from the Institute of Immunity and Transplantation, UCL Division of Infection and Immunity, Royal Free Hospital, London have published the research: LPS promotes a monocyte phenotype permissive for human cytomegalovirus immediate-early gene expression upon infection but not reactivation from latency, in the Journal: Scientific Reports Scientific Reports of 21/03/2017
• what: The authors report that triggers phenotype permissiveness for lytic infection directly correlating with concentration. The rationale for this approach was driven by a previous study in the murine system which showed that circulating monocytes rapidly populated the DC . . .
  

   

  

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