HIGHLIGHTS
- who: Benoit Langlois from the University of Colorado Anschutz Medical Campus, United States have published the paper: LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion, in the Journal: (JOURNAL)
- what: The authors identified for the first time the regulation of calpain activity as a new mechanism by which LRP1 controls the spreading and migratory capacities of thyroid carcinoma cells.
- how: The authors showed by three independent biochemical assessments that LRP-1 silencing leads to a significant induction of intracellular calpain activity in thyroid carcinoma . . .
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