HIGHLIGHTS
- who: Crystal Pan from the of California, Los Angeles, Los Angeles, CA, USA Department of Neurology, David Geffen School of Medicine, University have published the research work: LRP1: a novel receptor for the transmission of pathological u03b1-Synuclein, in the Journal: (JOURNAL)
- future: Future studies should further explore how LRP1 deletion affects u03b1-syn oligomer and fibril transmission in_vivo.
SUMMARY
Given that HSPGs have been reported to mediate the endocytosis of pathological α-syn, LRP1, as a co-receptor for HSPGs, could also play a critical role in the transmission of pathological . . .
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