Lrp1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin ii-mediated signaling

HIGHLIGHTS

  • who: Strickland and Dudley from the Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, USA have published the research work: LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II-mediated signaling, in the Journal: (JOURNAL)
  • what: The aim of this investigation was to define molecular mechanisms by which LRP1 protects against aneurysm formation in this vessel bed. The authors propose that LRP1 protects excessive remodeling of the SMA by regulating SMC phenotype and by attenuating AngII-mediated signaling.
  • how: To test the hypothesis that . . .

     

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