HIGHLIGHTS
- who: Houhong Wang et al. from the University Hospital Mu00fcnster, Germany have published the Article: LRPPRC facilitates tumor progression and immune evasion through upregulation of m6A modification of PD-L1 mRNA in hepatocellular carcinoma, in the Journal: (JOURNAL)
- what: This work assessed the regulatory effect of LRPPRC on the overall m6A modification in HepG2 and Hep3B cells. This work demonstrated that LRPPRC upregulated PDL1 mRNA in HCC with an m6A-independent manner.
SUMMARY
In HCC, LRPPRC upregulation correlates to decreased T_cells, cytotoxic cells, dendritic cells as well as cytolytic activity response . . .
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