Lsd1/prmt6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice

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  • who: Ramachandran Prakasam from the finally at , u00b0C for , minThe DNA was then amplified by using the MyTaq HS Red Mix, x and the human AR pair of primers (AR Q mice: Forward, u2032-CTTCTGGCGTGTGACCGGCG, reverse, u2032-TGAGC TTGGCTGAATCTTCC have published the paper: LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice, in the Journal: (JOURNAL) of 16/02/2022
  • what: Leveraging cell lines, mice, and patient-derived specimens, the authors show that androgen receptor co-regulators lysine-specific demethylase 1 (LSD1 . . .

     

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