Lung inflammation is associated with preeclampsia development in the rat

HIGHLIGHTS

  • who: Katrina Curtis and collaborators from the Placenta Laboratory, Department of Cell Biology and Physiology, Brigham Young University have published the paper: Lung Inflammation Is Associated with Preeclampsia Development in the Rat, in the Journal: Cells 2022, 1884 of 10/06/2022
  • what: This model showed PE-like characteristics including increased blood pressure, increased proteinuria, increased placental-derived inflammation, decreased trophoblast invasion, and an increase in placental apoptosis (gas6 paper).
  • how: To determine inflammatory profiles the authors conducted BALF experiments to initially evaluate to what extent Gas6 treatment contributed to lung inflammation.
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