Ly6d+siglec-h+ precursors contribute to conventional dendritic cells via a zbtb46+ly6d+ intermediary stage

HIGHLIGHTS

• who: Konstantin Lutz from the Institute for Immunology, Biomedical Center, LMU Munich, Grou00dfhaderner Str9, Planegg-Martinsried, Germany. Technical University have published the Article: Ly6D+Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+Ly6D+ intermediary stage, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors investigate the heterogeneity and commitment of DC precursor subsets using single-cell_RNA_sequencing and trajectory inference from RNA velocity combined with cell fate analysis. The authors show that type I IFN also influenced pDC versus cDC differentiation at a later stage in Ly6D+Siglec-H+ CD11c+CCR9lo precursors . . .
  

   

  

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