HIGHLIGHTS
- who: Jaekwan Kim and colleagues from the Duke University Medical Center, United States have published the Article: Lysine methyltransferase Kmt2d regulates naive CD8+ T cell activation-induced survival, in the Journal: (JOURNAL)
- what: The authors investigated the role of Kmt2d in CD8+ T_cell activation and apoptosis using T-cell specific Kmt2d knockout model.
- how: Increased expression and activity of apoptosis mediators in CD8+ T_cells from Kmt2d KO mice To determine the mechanisms of increased apoptosis the authors analyzed key cell death related genes (CD95 or Fas and Caspase activity). Flow cytometry data was . . .
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