HIGHLIGHTS
- who: Trine L. Toft-Bertelsen from the Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark have published the article: Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1, in the Journal: (JOURNAL)
- what: The authors demonstrate that LPA is indeed elevated in patients with subarachnoid haemorrhage (SAH) and in an animal model of IVH and reveal its ability to directly modulate the ion_channel TRPV4, which subsequently promotes NKCC1-mediated CSF hypersecretion and ventriculomegaly. The authors report that the . . .
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