Lysyl oxidase family proteins: prospective therapeutic targets in cancer

HIGHLIGHTS

  • who: Wei Wang and colleagues from the Department of Hepatobiliary and Pancreatic Surgery, Shanghai Sixth People`s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China have published the paper: Lysyl Oxidase Family Proteins: Prospective Therapeutic Targets in Cancer, in the Journal: (JOURNAL)
  • what: The experiment showed that Escin Ia, the main effective component in SFAC, can reduce LOXL2 activity and promote E-cadherin expression, thereby inhibiting the EMT process of TNBC .
  • future: More studies are still required because of the tissue-specific spatial and temporal differences in the expression . . .

     

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