M2-macrophage-derived exosomes promote meningioma progression through tgf- β signaling pathway

HIGHLIGHTS

  • who: M and colleagues from the Department, China Hospital, Sichuan University, Chengdu, China have published the research work: M2-Macrophage-Derived Exosomes Promote Meningioma Progression through TGF- u03b2 Signaling Pathway, in the Journal: Journal of Immunology Research of 20/05/2022
  • what: The authors aimed to discover a novel regulatory pathway by which exosome-mediated M2-polarized macrophages participate in tumorigenesis and progression. The study showed that M2-MDEs promoted development and invasion by activating the TGF-u03b2 signaling pathway. In short, the study demonstrates that M2MDEs play a promoting role in meningioma tumorigenesis, which . . .

     

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