M6a eraser fto modulates autophagy by targeting sqstm1/p62 in the prevention of canagliflozin against renal fibrosis

HIGHLIGHTS

  • who: Youjing Yang et al. from the Southwest Medical University, China have published the research work: m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis, in the Journal: (JOURNAL)
  • what: Consistently, in the study , the authors found a close association between SQSTM1 and autophagy through bioinformatic analysis and showed that SQSTM1 knockdown inhibited autophagy induced by Cana in HK2 cells.
  • how: All experiments were conducted in accordance with the Guide for the Care and Use of Laboratory Animals and the study protocols were approved by . . .

     

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