HIGHLIGHTS
SUMMARY
This study aimed to systematically evaluate the modification patterns of m6A RNA methylation in patients with CHD by using bioinformatics to analyse CHD sequencing data from the Gene Expression Omnibus (GEO) database. The infiltration of immune cells in the different m6A patterns was further analyzed to illustrate the impacts of m6A RNA modification on the immune environment of CHD. The "writers" are m6A methyltransferases that catalyse the formation of the m6A modification, while the "erasers" are m6A demethylases that regulate the demethylation of the m6A modification. M6A RNA modification exerts diverse functions in normal . . .
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