Macrophage differentiation is marked by increased abundance of the mrna 3’ end processing machinery, altered poly(a) site usage, and sensitivity to the level of cstf64

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  • who: Srimoyee Mukherjee and colleagues from the University of Surrey, United Kingdom have published the Article: Macrophage differentiation is marked by increased abundance of the mRNA 3u2019 end processing machinery, altered poly(A) site usage, and sensitivity to the level of CstF64, in the Journal: (JOURNAL)
  • what: This approach has been remarkably successful for a small subset of AML cases involving a PML-retinoic acid receptor fusion , and is a valuable alternative approach to killing cancer cells through cytotoxicity. The authors focused on CstF64, because it has been shown to influence APA during several types . . .

     

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