Macrophage-mediated inflammation in skin wound healing

HIGHLIGHTS

  • who: Alireza Hassanshahi and colleagues from the Regenerative Medicine, Future Industries Institute, University of South Australia, Adelaide, SA, Australia have published the research: Macrophage-Mediated Inflammation in Skin Wound Healing, in the Journal: Cells 2022, 11, 2953. of /2022/
  • what: Using single-cell_RNA_sequencing of human wound tissue, this study showed (COX-2/PGE2)-mediated NFu03baB-activated inflammation of M1 macrophages.
  • future: Collectively macrophages are key players in skin wound healing and further studies are required to elaborate how targeting macrophages can effectively improve skin wound healing in different pathophysiological conditions.

SUMMARY . . .

 

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