Macrophage-targeted anti-ccl2 immunotherapy enhances tumor sensitivity to 5-fluorouracil in a balb/c-ct26 murine colon carcinoma model measured using diffuse reflectance spectroscopy

HIGHLIGHTS

• who: Shelby N. Bess from the All animal experiments were approved by the University of Arkansas Institutional Animal Care and Use Committee (IACUC #, and #21014) and carried out in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals and the ARRIVE guidelinesAll efforts were made to minimize animal suffering and to reduce the number of mice used. Nine-week-old female Balb/c mice (n=95) were obtained from The Jackson Laboratory (Bar Harbor, ME, USA). Upon arrival, mice were housed in groups of three at , u00b0C u00b1 , u00b0C and . . .
  

   

  

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