Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles*

HIGHLIGHTS

• who: Rostyslav O. Bilyy from the (UNIVERSITY) have published the article: Macrophages Discriminate Glycosylation Patterns of Apoptotic Cell-derived Microparticles*, in the Journal: (JOURNAL) of June/17,/2011
• what: The authors propose that (i) apoptozing cells may change the glycosylation of de novo synthesized glycoconjugates. (ii) internal membranes containing immature glycoproteins (GP) may become exposed and_(iii) mature GP may get modified by glycosidases (e_g sialidases) in situ. The authors demonstrate that apoptotic cells release distinct types of scMP derived from endoplasmic_reticulum (ER) or plasma_membrane. As Neu2 is exclusively expressed in muscle and Neu3/4 . . .
  

   

  

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