Mad1 influences interphase nucleoplasm organization and chromatin regulation in drosophila

HIGHLIGHTS

• who: Tpr and collaborators from the CNRS, Institut Jacques Monod, UMR7592, Université Paris Diderot, Sorbonne Paris Cité, Paris , France have published the article: Mad1 influences interphase nucleoplasm organization and chromatin regulation in Drosophila, in the Journal: (JOURNAL) of 16/07/2022
• what: Rsob.royalsocietypublishing.org Here the authors report that, in Drosophila, Mad1 localizes to intranuclear structures in many cell types, including terminally differentiated postmitotic cells.

SUMMARY

Kinetochore-bound Mad1 acts as a catalyst, helping the protein Mad2 bind to the mitotic regulator Cdc20 and thus generate the anaphase inhibitor. In . . .

 



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