HIGHLIGHTS
- who: Satoru Matsuda and Yasuko Kitagishi from the Department of Food Science and Nutrition, Nara Women`s University, Japan have published the Article: MAGI Scaffolding Molecules Involved in Cancer Cell Signaling, in the Journal: (JOURNAL)
SUMMARY
The PTEN interacts with PDZ domain-containing molecules including MAGI proteins (MAGIs), which are scaffolding molecules involved in the regulation of tight-junction assembly and are then involved in diverse regulatory pathways including the control of cell-attachment. PTEN plays a critical role in MAGIs-induced inhibition of cell migration and proliferation in cancers. Germ line mutations . . .
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