Maintenance of epigenetic landscape requires ciz1 and is corrupted in differentiated fibroblasts in long-term culture

HIGHLIGHTS

• who: Emma R. Stewart from the University of have published the paper: Maintenance of epigenetic landscape requires CIZ1 and is corrupted in differentiated fibroblasts in long-term culture, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors focus here on the small fraction of cells (3-7% depending on cell line and rate of cycling) that resist extraction with RNase so that CIZ1 remains anchored at Xi (Fig 1a, b). The authors show that the majority of the 65,530 transcription units that align to the rest of mouse genome assembly GRCm38 are also . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.