Maintenance of hypoimmunogenic features via regulation of endogenous antigen processing and presentation machinery

HIGHLIGHTS

• who: Endogenous Antigen Processing and colleagues from the Department of Functional Genomics, KRIBB School of Bioscience, University of Science and Science Center, United States have published the research: Maintenance of Hypoimmunogenic Features via Regulation of Endogenous Antigen Processing and Presentation Machinery, in the Journal: (JOURNAL)
• what: The authors showed that the hypoimmunogenic properties of gene-edited cell lines can be disrupted by epigenetic factors that arose during differentiation into functional derivatives and can be retained by overexpression of the transcription factors, RelA and NLRC5.
• future: Further work is needed to enhance the utility . . .
  

   

  

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