HIGHLIGHTS
- who: A. Pham from the , Paris, France have published the paper: Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells, in the Journal: (JOURNAL)
- what: The authors report, for the first time, an extensive analysis of methylation levels of several ICRs involved in human IDs in iPSCs. The authors show that the culture of iPSCs under hypoxia prevents aberrant hypermethylation of ICRs in iPSCs derived from controls and patient with ID.
- how: The authors identified polymorphisms in IGF2 (rs3168310) and DLK1 (rs1802710) in the genomic DNA of C1 . . .
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