Mait cells detect and efficiently lyse bacterially- infected epithelial cells

HIGHLIGHTS

• who: Lionel Le Bourhis and collaborators from the labellisée de la ligue de lutte contre cancer, Institut Curie, Paris, France have published the paper: MAIT Cells Detect and Efficiently Lyse Bacterially- Infected Epithelial Cells, in the Journal: (JOURNAL) of October/10,/2013
• what: The authors show that MAIT cells display cytotoxic activity towards MR1 overexpressing non-hematopoietic cells cocultured with bacteria. The authors show that MAIT_cells recognize epithelial_cells infected by the intestinal pathogen Shigella flexneri in a process requiring endogenous MR1, while the closely related bacterium Salmonella Tyhpimurium is not. The authors provide evidence . . .
  

   

  

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