Major target for uv-induced complete loss of hiv-1 infectivity: a model study of single-stranded rna enveloped viruses

HIGHLIGHTS

  • who: Takaaki Koma from the United States Guangzhou Medical University, China have published the research: Major target for UV-induced complete loss of HIV-1 infectivity: A model study of single-stranded RNA enveloped viruses, in the Journal: (JOURNAL)
  • what: Through virological analyses, the authors demonstrate that UV can have an effect on the enzymatic activity of a viral protein but not the entry process at all, and that the loss of viral infectivity principally results from UV-induced genome damage. The authors showed that HIV-1 is inactivated even without apparent destruction of proteins . . .

     

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