Make or break: the thermodynamic equilibrium of polyphosphate kinase-catalysed reactions

HIGHLIGHTS

  • who: Michael Keppler and colleagues from the Institute of Pharmaceutical Sciences, University of Freiburg, Germany have published the research work: Make or break: the thermodynamic equilibrium of polyphosphate kinase-catalysed reactions, in the Journal: (JOURNAL)
  • what: The authors analysed a set of well-known PPK enzymes regarding the thermodynamic equilibrium of ATP syn- thesis and compared the experimental results obtained with theoretical calculations. The consequence of this assumption is that interactions among nucleotides and polyP were considered to be equal to interactions among nucleotides and polyPn-1, and the authors focused only on the ratio . . .

     

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