Making sense of the literature on antipsychotics and long-term functioning: taking natural history and personalization seriously

HIGHLIGHTS

• What: Rather than offering a comprehensive or systematic review of research studies, the focus of this paper will be on a few key studies that exemplify broader trends in the literature and will illustrate how they can be clinically interpreted with attention to the natural history of these disorders and the need for individualized treatment. Randomized studies in this meta-analysis were of higher quality and favored maintenance treatment but they were short-term ( and amp;lt;2 years), while longer studies in this review were non-randomized, evaluated by authors as being of lower quality, and . . .
  

   

  

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