Malt1 regulates th2 and th17 differentiation via nf-κb and jnk pathways, as well as correlates with disease activity and treatment outcome in rheumatoid arthritis

HIGHLIGHTS

  • who: Qiubo Wang and collaborators from the Affairs, United States have published the research work: MALT1 regulates Th2 and Th17 differentiation via NF-κB and JNK pathways, as well as correlates with disease activity and treatment outcome in rheumatoid arthritis, in the Journal: (JOURNAL)
  • what: Receiver operating characteristic (ROC) analysis was carried out to evaluate the ability of MALT1 in distinguishing different subjects.

SUMMARY

    MALT1 relates to CD4 + T_cell subpopulations and is dysregulated in RA. Although the detailed pathogenesis of RA is still unclear, genetic factors, aberrant autoimmune antibodies (rheumatoid factor . . .

     

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