Mammalian hbs1l deficiency causes congenital anomalies and developmental delay associated with pelota depletion and 80s monosome accumulation

HIGHLIGHTS

  • who: Amy E. O#_#x2019 et al. from the Editor: SBarsh, Stanford University have published the research work: Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation, in the Journal: (JOURNAL)
  • what: The authors show that deficiency of Hbs1L:Pelota complex leads to increased levels of 80S ribosomal monosomes as well as an increase in translation of ribosomal RNA.
  • how: Protein expression data was analyzed using Quantity One software (v. 4.2.1 Bio-Rad Laboratories Hercules CA USA). When replicates were sufficient as . . .

     

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