Mammary adipocytes protect triple-negative breast cancer cells from ferroptosis

HIGHLIGHTS

  • who: Yizhao Xie from the (UNIVERSITY) have published the research: Mammary adipocytes protect triple-negative breast cancer cells from ferroptosis, in the Journal: (JOURNAL)
  • what: This study reveals the protection of adipocytes against breast cancer ferroptosis through MUFA production requiring ACSL3.

SUMMARY

    The authors first established the mammary adipocyte-breast cancer cell co-culture system. Mature adipocytes were derived and separated from patients underwent breast cancer surgery and an isolated co-culture system was established using transwell culture dish where adipocyte was in upper level and breast cancer cell was in . . .

     

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