HIGHLIGHTS
- who: Chen Chen and colleagues from the Xiangya Hospital, Central South University, China have published the research work: Manipulating T-cell metabolism to enhance immunotherapy in solid tumor, in the Journal: (JOURNAL)
- what: __SECTION__ 7.1 Metabolic modulation to enhance.
- future: Validation study is still needed to guide precision medicine.
SUMMARY
The stimulation of resting T_cells promotes the conversion of catabolic and oxidative metabolism to aerobic glycolysis in effector T_cells, and subsequently back to oxidative metabolism in memory T_cells. Taken together, tumor cells always choose the optimal metabolic pattern . . .
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