Manipulation of topoisomerase expression inhibits cell division but not growth and reveals a distinctive promoter structure in synechocystis

HIGHLIGHTS

  • who: Lutz C. Berwanger and colleagues from the Institut fSynthetische Mikrobiologie, , (CEPLAS), , Germany have published the research: Manipulation of topoisomerase expression inhibits cell division but not growth and reveals a distinctive promoter structure in Synechocystis, in the Journal: (JOURNAL)
  • what: Based on the current models of the role of DNA_supercoiling homeostasis in bacteria , the authors hypothesized that artificial genome relaxation should inhibit growth and redirect metabolic flux. Next, the authors focused on the core promoter . The authors provide the first observation of a direct alignment of the TSS and the -10 element with helical phased . . .

     

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