Mannose trimming targets mutant α2-plasmin inhibitor for degradation by the proteasome*

HIGHLIGHTS

• who: Dong Hui Chung from the (UNIVERSITY) have published the article: Mannose Trimming Targets Mutant α2-Plasmin Inhibitor for Degradation by the Proteasome*, in the Journal: (JOURNAL) of July/26,/1999
• what: The authors demonstrate that mutant ␣2PI proteins are degraded by proteasomes. The lysosomal protease inhibitors used in this experiment had no effect on the total amount of radioactivity in the cell extracts after the 6-h chase period. In the study , it was shown that mannose trimming of the mutant ␣2PI proteins that have dissociated from CNX is a very important process in . . .
  

   

  

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