Marine polyether phycotoxin palytoxin induces apoptotic cell death via mcl-1 and bcl-2 downregulation

HIGHLIGHTS

• who: Jaemyun Kim and collaborators from the Department of Pharmacy, College of Pharmacy, Seoul National University, Gwanak-gu, Institut Mu00e9diterranu00e9en d`Ocu00e9anologie, de Luminy, , Marseille, France have published the paper: Marine Polyether Phycotoxin Palytoxin Induces Apoptotic Cell Death via Mcl-1 and Bcl-2 Downregulation, in the Journal: (JOURNAL)
• what: Altogether the authors provide evidence of the role of palytoxin as a very potent and promising anti-leukemic agent acting at low picomolar concentrations in cellulo and in vivo. Palytoxin lipophilic and regions and is considered a super-carbon-chain compound with the longestMoreover, chain . . .
  

   

  

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