Markov state models reveal a two-step mechanism of mirna loading into the human argonaute protein: selective binding followed by structural re-arrangement

HIGHLIGHTS

• who: Hanlun Jiang and collaborators from the Editor: Shi-Jie Chen, University of Missouri, UNITED d'Informatique de l'École Polytechnique (LIX), CNRS UMR, École Polytechnique, Palaiseau, France have published the research work: Markov State Models Reveal a Two-Step Mechanism of miRNA Loading into the Human Argonaute Protein: Selective Binding followed by Structural Re-arrangement, in the Journal: (JOURNAL) of July/16,/2015
• what: The authors propose a two-step mechanism for this molecular recognition: selective binding followed by structural re-arrangement. The model has been further validated by residence probability test , in which . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.