Mass spectrometry-based metabolomics revealed effects of metronidazole on giardia duodenalis

HIGHLIGHTS

  • who: Supaluk Popruk and colleagues from the Department of Protozoology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand have published the article: Mass Spectrometry-Based Metabolomics Revealed Effects of Metronidazole on Giardia duodenalis, in the Journal: Pharmaceuticals 2023, 408 of /2023/
  • what: This study demonstrated in_vitro antiparasitic activity of metronidazole with an IC50 value of 2.013 u00b1 0.35 u00b5g/mL (11.67 u00b5M). This research provided a better understanding of the effects of metronidazole via G. duodenalis proteasome and glycerophospholipid metabolisms.
  • how: The authors applied a mass spectrometry-based metabolomics analysis . . .

     

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