Mast cell activation mediates blood–brain barrier impairment and cognitive dysfunction in septic mice in a histamine-dependent pathway

HIGHLIGHTS

• who: Jianhe Yue and colleagues from the Yunnan Agricultural University, China have published the article: Mast cell activation mediates bloodu2013brain barrier impairment and cognitive dysfunction in septic mice in a histamine-dependent pathway, in the Journal: (JOURNAL)
• what: The authors aimed to investigate the important roles of abnormally activated MCs in cecal ligation puncture (CLP)-induced encephalopathy. This work provides preliminary evidence for the protective Frontiers in Immunology
• how: Results showed that MCs were overactivated in the hippocampus of CLPinduced SAE mice. The results showed that the expression level of tryptase increased significantly . . .
  

   

  

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