HIGHLIGHTS
- who: Chao Li from the (UNIVERSITY) have published the Article: Master microRNA-222 regulates cardiac microRNA maturation and triggers Tetralogy of Fallot, in the Journal: (JOURNAL) of 21/03/2022
- how: These in_vivo data showed that enoxacin and Fer-1 effectively prevent mir-222-induced TOFrelated cardiac defects. The authors identified miR-222 as a master regulator of cardiac miRNA maturation/dosage and demonstrated connections among high levels of miR-222 cardiac hypertrophy ferroptosis in mouse models and fetuses with TOF (Fig 1w).
SUMMARY
Markers of cardiomyocyte hypertrophy increased in response . . .
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