Maternal blood pressure associates with placental dna methylation both directly and through alterations in cell-type composition

HIGHLIGHTS

  • who: Lucile Brosu00e9us from the University Grenoble Alpes, INSERM, Team of Environmental Epidemiology Biosciences (IAB), Grenoble, France have published the Article: Maternal blood pressure associates with placental DNA methylation both directly and through alterations in cell-type composition, in the Journal: (JOURNAL)
  • what: For DNAm is thought to be involved in the regulation of gene_expression, the approach had a focus on DMRs located nearby known genes.
  • how: The authors hypothesized that maternal BP could influence placental DNAm and taking advantage of recent experimental advances to estimate the proportion of six reference cell types . . .

     

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