Maternal dexamethasone exposure induces sex-specific changes in histomorphology and redox homeostasis of rat placenta

HIGHLIGHTS

SUMMARY

    The authors observed sex-specific changes in the morphological features and/or susceptibility of placentas to oxidative stress following maternal Dx exposure, which was used as a model of a challenging prenatal environment. Maternal Dx exposure between embryonic day (E) 16 and 18 resulted in significant (p and amp;lt; 0.05) fetal growth restriction and a reduction in the average weight of their placentas measured on E 21. Fetal weight Placental weight Placental to fetal Weight ratio Male -Control (g ± SD) 5 ± 0.04 0.62 ± 0.06 Female-Control (g ± SD) 4 . . .

     

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