HIGHLIGHTS
- who: January et al. from the Zhengzhou University, China have published the paper: Maternal sevo urane exposure induces neurotoxicity in offspring rats the CB1R/CDK5/p-tau pathway, in the Journal: (JOURNAL)
- what: The data obtained from the research demonstrated that 3.5% sevoflurane exposure of maternal rats activated CB1R/CDK5/p25/p-tau pathway in the hippocampus of fetuses and offspring rats, resulting in diminishment in neuron and dendritic spine densities in the hippocampal CA1 area. The research provides an important theoretical basis for the development of new drugs targeting CB1R.
- how . . .
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