Mathematical models for biomarker calculation of drug-induced liver injury in humans and experimental models based on gadoxetate enhanced magnetic resonance imaging

HIGHLIGHTS

  • who: Markus Karlsson and collaborators from the Editor:, Heidelberg University have published the paper: Mathematical models for biomarker calculation of drug-induced liver injury in humans and experimental models based on gadoxetate enhanced magnetic resonance imaging, in the Journal: PLOS ONE of 26/05/2021
  • what: Predicting human liver function Conclusions the analysis provides clear guidelines of which model to use for model-based assessment of biomarkers for liver function and it also suggests a hypothetical path to a translational framework for DILI. The authors aimed to investigate three different mathematical models with respect to . . .

     

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