Matrix metalloproteinase-2 knockout and heterozygote mice are protected from hydronephrosis and kidney fibrosis after unilateral ureteral obstruction

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  • who: Maria K. TveitarĂ„s et al. from the Department of Biomedicine, University of Bergen, Bergen, Department of Clinical Medicine have published the article: Matrix Metalloproteinase-2 Knockout and Heterozygote Mice Are Protected from Hydronephrosis and Kidney Fibrosis after Unilateral Ureteral Obstruction, in the Journal: PLOS ONE | DOI:10.1371/journal.pone [0143390]. December 16, 2015 of /1371/
  • what: The authors investigated the effect of UUO on gene expression fibrosis and pelvic remodeling in the kidneys of Mmp2 deficient (Mmp2-/-) heterozygous animals (Mmp2+/-) and wild-type (Mmp2+/+). The experiments were conducted in accordance with the . . .

     

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