Matrix metalloproteinases in chronic obstructivepulmonary disease

HIGHLIGHTS

  • who: Maria-Elpida Christopoulou et al. from the Department of Pneumology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany have published the paper: Matrix Metalloproteinases in Chronic ObstructivePulmonary Disease, in the Journal: (JOURNAL)
  • future: Studies should be conducted to clarify the role of TIMP-4 in the pathogenesis of COPD.

SUMMARY

    Type V collagen is hydrolyzed by MMP-2 and MMP-9 but not MMP-1, MMP-8 or MMP-13, whereas type XI collagen is cleaved by MMP-1, MMP-2 and MMP-9 but not by MMP . . .

     

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