Matrix remodeling associated 7 proteins promote cutaneous wound healing through vimentin in coordinating fibroblast functions

HIGHLIGHTS

  • who: Ying Shen from the Institute of Hematology, The First Affiliated Hospital of Soochow, Soochow, China have published the paper: Matrix remodeling associated 7 proteins promote cutaneous wound healing through vimentin in coordinating fibroblast functions, in the Journal: (JOURNAL)
  • how: Showed that the deficiency impaired the process in mice. Cell spreading assay was performed to compare the adhesion of M u00ad XRA7-/- and WT fibroblast to collagens and the results showed that MXRA7 deficiency enhanced fibroblast adhesion (Fig 3f g).
  • future: Future studies should define how MXRA7 proteins interact with well-known ECM . . .

     

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