Mature myotubes generated from human-induced pluripotent stem cells without forced gene expression

HIGHLIGHTS

  • who: Kei Fujiwara and collaborators from the Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan, Clinical Neurophysiology, Department of have published the paper: Mature Myotubes Generated From Human-Induced Pluripotent Stem Cells Without Forced Gene Expression, in the Journal: (JOURNAL)
  • what: Transient Na+ currents recorded from Pax7-Venus iMuSC-derived myotubes in this study showed that the voltage dependence of activation was more depolarized than that from hiPSC-derived cardiac myotubes (Selga et_al, 2018). The authors aim to develop a more simple method to generate screening applicable mature myotubes from hiPSCs . . .

     

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