Maximum depth sequencing reveals an on/off replication slippage switch and apparent in vivo selection for bifidobacterial pilus expression

HIGHLIGHTS

  • who: Christophe Penno from the School University College have published the paper: Maximum depth sequencing reveals an ON/OFF replication slippage switch and apparent in vivo selection for bifidobacterial pilus expression, in the Journal: Scientific Reports Scientific Reports
  • what: The authors investigated an as yet unexplored aspect of micro-diversity generation in members of the genus Bifidobacterium involving the bacterial DNA_polymerase. 3- For the first time the authors show that replication slippage at a G-tract seems to be subject to in_vivo modulation generating an enrichment of bacteria which would ultimately express sortase-dependent pili . . .

     

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