Measuring and interpreting nuclear transport in neurodegenerative disease—the example of c9orf72 als

HIGHLIGHTS

  • who: Marije F. W. Semmelink et al. from the European Research Institute for the Biology of Ageing, University of Groningen have published the paper: Measuring and Interpreting Nuclear Transport in Neurodegenerative Disease—The Example of C9orf72 ALS, in the Journal: (JOURNAL)
  • future: Answering this open question has far-reaching implications because a positive answer would imply that widespread mislocalization of proteins occurs far beyond the reported mislocalization of transport reporters and specific proteins such as FUS or TDP43 and thus presents a challenge for future research. For future studies the choice of model systems is . . .

     

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